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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLNS1A
All Species:
0
Human Site:
S117
Identified Species:
0
UniProt:
P54105
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54105
NP_001284.1
237
26215
S117
T
E
F
R
F
V
P
S
D
K
S
A
L
E
A
Chimpanzee
Pan troglodytes
XP_001175048
222
24569
I109
S
D
D
D
V
E
P
I
T
E
F
R
F
V
P
Rhesus Macaque
Macaca mulatta
XP_001088333
203
22330
A90
N
A
K
F
E
V
E
A
M
F
T
A
M
C
E
Dog
Lupus familis
XP_535567
226
24585
A113
S
D
K
S
A
L
E
A
M
F
T
A
M
C
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61189
236
26003
D117
E
F
R
F
V
P
S
D
K
S
A
L
E
A
M
Rat
Rattus norvegicus
Q04753
236
26074
D117
E
F
R
F
V
P
S
D
K
S
A
L
E
A
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519221
278
30242
G125
A
E
F
R
F
V
P
G
D
R
S
A
L
E
A
Chicken
Gallus gallus
XP_423253
238
26615
V115
P
I
A
E
F
R
F
V
P
S
D
K
S
A
L
Frog
Xenopus laevis
P54106
241
26428
I115
D
E
E
P
I
T
E
I
R
F
V
P
G
E
K
Zebra Danio
Brachydanio rerio
NP_571499
249
27316
I115
D
S
E
G
S
G
E
I
T
E
I
R
F
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611237
215
23724
G102
V
N
G
R
N
G
G
G
S
E
A
E
V
D
E
Honey Bee
Apis mellifera
XP_624081
207
23224
P94
L
P
D
V
S
L
S
P
A
S
D
S
G
S
E
Nematode Worm
Caenorhab. elegans
NP_001021287
205
22895
A92
K
S
G
L
E
L
A
A
A
E
L
E
D
E
E
Sea Urchin
Strong. purpuratus
XP_001194575
165
18108
P52
M
S
E
L
R
D
V
P
G
H
G
G
D
G
P
Poplar Tree
Populus trichocarpa
XP_002318279
231
25740
A117
S
D
S
E
C
S
D
A
L
D
L
S
K
V
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.2
85.6
82.2
N.A.
90.3
90.3
N.A.
40.6
82.3
72.1
68.2
N.A.
20.2
40
29.9
24.4
Protein Similarity:
100
93.2
85.6
85.2
N.A.
94.9
94.9
N.A.
53.2
90.3
82.5
80.3
N.A.
37.5
56.5
45.5
40.9
P-Site Identity:
100
6.6
13.3
6.6
N.A.
0
0
N.A.
80
6.6
13.3
0
N.A.
6.6
0
6.6
0
P-Site Similarity:
100
26.6
33.3
46.6
N.A.
6.6
6.6
N.A.
86.6
6.6
13.3
6.6
N.A.
33.3
13.3
26.6
0
Percent
Protein Identity:
25.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
48.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
0
7
0
7
27
14
0
20
27
0
20
14
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
14
0
% C
% Asp:
14
20
14
7
0
7
7
14
14
7
14
0
14
7
0
% D
% Glu:
14
20
20
14
14
7
27
0
0
27
0
14
14
27
34
% E
% Phe:
0
14
14
20
20
0
7
0
0
20
7
0
14
0
0
% F
% Gly:
0
0
14
7
0
14
7
14
7
0
7
7
14
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
7
0
0
7
0
0
20
0
0
7
0
0
0
0
% I
% Lys:
7
0
14
0
0
0
0
0
14
7
0
7
7
0
7
% K
% Leu:
7
0
0
14
0
20
0
0
7
0
14
14
14
0
7
% L
% Met:
7
0
0
0
0
0
0
0
14
0
0
0
14
0
14
% M
% Asn:
7
7
0
0
7
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
7
7
0
7
0
14
20
14
7
0
0
7
0
0
20
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
14
20
7
7
0
0
7
7
0
14
0
0
0
% R
% Ser:
20
20
7
7
14
7
20
7
7
27
14
14
7
7
0
% S
% Thr:
7
0
0
0
0
7
0
0
14
0
14
0
0
0
7
% T
% Val:
7
0
0
7
20
20
7
7
0
0
7
0
7
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _